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Fatal sexually transmitted disease, syphilis -------------------------------------------------- ------------------------------ ■ Introduction: Spirochaete (spirochete) Treponema pallidum is argued by the spread mainly by seongjeopchoke which may involve any organ is a systemic disease. Very diverse and the clinical phase, AIDS and the increased use of antibiotics increasingly mild or atypical syphilis patients are increasingly taking over. ■ Symptoms: Clinically, many stages, incubation period (incubation period), 1 syphilis (primary syphilis), 2 syphilis (secondary syphilis), latent syphilis (latent syphilis), late syphilis (late syphilis) is. 3 Reviews syphilis syphilis (tertiary syphilis), also known as neural syphilis (neurosyphilis), cardiovascular syphilis (cardiovasculr syphilis), gomujong (gumma) appears to be. 1 syphilis The incubation period after infection, a lesion of syphilis (chancre), the average period of three weeks to appear (3-90 days), and the number of bacteria per 1 gm tissue, and once you have to be more than 107 divisions of time it takes 30-33 hours to is different depending on the amount initially inoculated. It appears that appear in all patients but also patients even if they are not. Typical of a syphilis lesion is a papule with no pain. Papules that are just ulcers, basal and features a clear boundary has been elevated as hard as cartilage. Secondary infection, ulcers, unless there is no clear fluid. There is no pain, there are pressing a little tenderness. For dark field microscopy and scratched the floor when the lesion is almost no pain or bleeding. This can cause multiple ulcers, atypical lesions, skin lesions appear or if there is no common. Chancre congenital syphilis except for the smoke does not appear to be. Location is determined by the inoculated area, the most common location is the extrinsic period, in women the cervix, mouth, anus, anal, gay men around the anus, anal, oral, also commonly appear. Oral and anal ulcers are infected with the two cars is common. Lymph node enlargement and a moderate big, solid, without a remedy, there is no pain, lesions are accompanied by a period. Chancre is 3-6 weeks (1-12 weeks) if you are naturally healing chancre had little or no trace of the atrophic area and leave scars. Lymphadenopathy is usually longer lasting. 2 syphilis 2 of syphilis vaccine 6 weeks (2-12 weeks) and then, or chancre occurring 2-8 weeks after this happens. Therefore, some patients are still in a period when there are lesions. Get a number in the body in the presence of H. Spiro, especially in the blood, it appears. With systemic symptoms and skin and mucous membrane lesions appear in all organs of body can be seen above. The host to generate immunity against Treponema pallidum H. Spiro continued until prevented the spread of other, and by immune complex lesions may appear. After 3-12 weeks are naturally aggressive. Clinical phase 2 of syphilis is very diverse and the most common skin lesions. Van (MACULE), papules (papule), pustules (pustule), nodules (nodule) comes out the various cases do not appear in vain. Start the trunk and proximal extremities and red colors pink colors 3 ~ 10 mm of bilateral appears banjinyi lasts from days to 8 weeks. The skin may appear in certain areas, palms and soles, especially if the rash of syphilis is s movement. If the involvement of hair follicles (follicular syphilids) temporary hair loss occurred, or out of your eyebrows and beard are thin. As banjineseo rarely papules pustules (pustular syphilids) also are ongoing. Endocarditis and perivascular lymphocyte infiltration of arteries also proceed at the same rate. Warm and damp skin overlap area (around the anus, a woman's vulva, scrotum, thigh inward, breast down, shins, aekwabuna forearms, and fingers or between the toes), the papule grows, they came together and pain free, a large pink in the Are you this edition of the formation of a gray flat condyloma (condyloma lata) is called, is very contagious and strong.MUCOUS patch include other highly contagious disease called mucosal lesions are caused. Lips, mouth, pharynx, tonsil, women vulva, vagina, penis, penis inside of the epidermis, erosions of the silvery gray of anal redness around it is typical.There is no pain. 2 Skin lesions during a recurrence of syphilis rather than the first but certainly not asymmetrically distributed, and more invasive enemy. Perhaps the host immune response may be due to the stronger it gets. Flat condyloma is very common. Systemic symptoms included fever, general boredom, sore throat, laryngitis, loss of appetite, weight loss, joint pain, they produce systemic lymphadenopathy. Involvement of the central nervous system and headaches, sumakjageukjeung (meningismus) that appear frequently in CSF protein and lymphocyte rise 8-33% of patients can be seen. 1-2% of acute aseptic meningitis occurs in patients. Even more than that in normal subjects were cured with antibiotic therapy for AIDS patients are not cured of syphilis indicate nerve. 3 stage syphilis occurs when a nerve different from the early neural syphilis (early neurosyphilis) uses the term. Latent syphilis Latent syphilis, syphilis of the normal CSF and no clinical findings, chest X-ray image that represents the top and if you are tested positive for treponema. Is the state of progress continues. Early latent syphilis can cause a recurrence can be infectious. Recurrence within 1 year if the first is 75-90% and 95% within 2 years, 5 years is 100%. Recurrence more than weakens the clinical phase. The most common mucosal recurrence. Recurrence of latent syphilis, late period does not (late latent syphilis) is called. Only the pregnant woman to the fetus through the placenta and can be propagated and spread to others by blood transfusion can be. Early and late breaks down artificial and 1-4 years time. Currently set forth in the United States, CDC uses a lot of years. Can a recurrence of periods beyond the differences in pathology and therapy, but infected animals, according to the longer treatment period would require increasing the amount of penicillin, so the amount of antibiotic is likely to vary. Late syphilis (late syphilis) or 3-stage syphilis (tertiary syphilis) Patients with late incubation period 1 / 4 ~ 1 / 3 of the findings appears 3rd VDRL titer syphilis are diverse. The main lesion of primary syphilis 3 aortic (approximately 10% of the rate), or central nervous system (the rate of approximately 8%) and other clinical type gomujong (gumma) in about 15% of patients occurs. Granulomatous lesions, skin, soft tissue, bone, liver, testicles, such as occurs in real organizations. Syphilis positive reviews (BENIGN tertiary syphilis) Gomujong (gumma) nonspecific chronic granulomatous inflammation mainly the skin (70%), bone (10%), mucous membranes occur in a certain tissue can occur. Occurs when an incomplete treatment. Is always positive for VDRL. Can occur, one or more, with varying sizes from microscopic lesions such as tumors are large. It grows very slowly, the main clinical findings shall be made by the long-term destruction of the local. Nodular skin lesions on the skin vary from deep granulomatous lesions and necrotic ulcers, as close to a pure form. Elapses, the more thin atrophic scars remain.Kinds of bone fractures or joints rubber can lead to the destruction of, and the nose and 9 kinds of rubber on the upper airway causes perforation. Trauma can occur in the receiving area. Spiro H. lesions are very difficult to find another, if you do not have any other disease and the differential in the experience dramatically improved when penicillin is used. Cardiovascular syphilis Obstructive coronary artery disease endocarditis is more than the default. Vasculature of the aortic vascular wall (vasa vasorum) and by involving the destruction of elastic fibers and causes necrosis of the aorta jungpiui. As a result, formation of aneurysms and aortic insufficiency and coronary artery stenosis causes. Symptomatic patients with aortic infection, untreated syphilis occurs in 10% of one, more than 35% in pathological studies.Chest X-ray image when the aortic wall calcification, such as lines and asymptomatic aortic maedokseong salt should be suspicious. If the hardening of the arteries due to calcification is rare. If aortic dissection maedokseong synovitis are rare.Central nervous system disorders in patients with cardiovascular syphilis is the most common findings. Nerve Syphilis Whether or not accompanied by symptoms of nervous syphilis is divided into. Mujeunghu increasing attention in recent syphilis, syphilis is very rare and was real nervous. Mujeunghu nerve syphilis (asymptomatic neurosyphilis) A diagnosis of clinical care and you do not have clinical findings of syphilis in CSF cell growth, increased protein, reduced sugar, VDRL positive findings, even if either one is possible.Untreated 8-33% of patients with syphilis in the nervous mujeunghu represents mujeunghu nervous symptoms in patients with syphilis, the ongoing incidence of syphilis may be nervous. The symptoms of nerve syphilis 2 Are large clinical meningeal vascular nerve syphilis categories (meningovascular neurosyphilis)) and the actual nerve syphilis (parenchymatous neurosyphilis) is. Meningeal veins meningeal nerve syphilis obstructive naehyeolgwanyeomyi, brain, spine and involvement of the tiny blood vessels that will be, the real nerve syphilis nerve cells, nerve cells of the cerebral cortex caused the destruction of means. Meningeal blood vessels so nerve inflammatory lesions, compared with the real nervous syphilis Syphilis is a degenerative disease. In fact, much of the other gyeopchimyeo, with pathological lesions in two cases jeokeurodo common. Meningeal blood vessels in nerve syphilis bancheukmabieseo progressive nerve damage that represent a wide range of clinical manifestations. If you have seizures that appear common. Substantial progress in syphilis nerve palsy (general PARESIS) and to the spinal cord (tabes dorsalis) is, and shall be subject to a wide range of real destruction. Progression of numbness or paralysis (paresis), depending on each spell so easy to remember - p (personality: personality), a (affect: emotions), r (reflexes: Reflection), e (EYE: eye - Argyll Robertson pupils) , s (sensorium: sensory - delusions, hallucinations), i (intellect: intelligent), s (speech: language) is. Fracture of the spine (tabes dorsalis) mainly posterior column, dorsal root, dorsal root ganglia as early dehydration, ataxia, foot Suddenly Leaving (footslap), paresthesia, "was electrocuted when the pain (lightening pain)" (a sudden start spreading the pain disappeared), bladder or erectile dysfunction, loss of position sense and vibration sense, deep sense of loss of copper through the temperature will appear. Romberg characteristic signs appear. Proliferative degenerative joint disease (Charcot's joints) and hajina traumatic foot ulcers appear.